Metribolone (also known as methyltrienolone (or 17α-methyltrenbolone), as well as 17α-methyl-19-nor-Δ9,11-testosterone or 17α-methyl-19-norandrosta-4,9,11-triene-17β-ol-3-one, is a highly potent, orally active, non-aromatizable anabolic-androgenic steroid (AAS) of the 19-nortestosterone and 17α-alkylated groups which was never marketed for clinical use but has been used in scientific research as a photoaffinity label for the androgen receptor (AR) and in AR ligand binding assays. It is the 17α-methylated derivative of trenbolone (trenbolone), and is a similarly potent AAS, but has a high potential for hepatotoxicity similarly to other 17α-alkylated AAS. Metribolone binds with high affinity not only to the AR but also to the progesterone receptor (PR), and binds to the glucocorticoid receptor (GR) as well. It is said to be the most potent AAS.
Metribolone, also known as methyltrienolone is a potent, non-aromatizable androgen which has also been used as a photoaffinity label for the androgen receptor. It is the 17-methylated derivative of trenbolone, and is a similarly potent anabolic steroid, but with high hepatotoxicity. Methyltrienolone binds strongly to the androgen receptor and is a more potent agonist (activator) of the androgen receptor than is DHT.
Metribolone binds onto the androgen receptor so strongly that it is pretty much the benchmark for that quality. Androgen Receptors are found in both fat cells as well as muscle cells; they act on the androgen receptor in muscle cells to promote growth, and in the fat cells to affect fat burning.The stronger the androgen binds to the androgen receptor, the higher the lipolytic fat burning effect on adipose fat tissue. Metribolone is basically a 17aa (oral) version of (injectable) Trenbolone. androgen receptor binding and androgen receptor stimulation is not the only mechanism which stimulates anabolism.
Metribolone is an anabolic steroid that is available for oral administration as tablets and is available also as injection. Generally, most of the users tend to take metribolone for a shorter period of time at the room temperature below 30 degrees C.
Metribolone is steroid hormone which can increase muscular endurance and explosive power,it is the most powerful anabolic steroids ever producedIt can also Treatment of advanced and recurrent breast cancer and ovarian cancer and other diseases.
Side Effects of Metribolone
It is also one of the most hepatotoxic androgens, or maybe the most toxic steroid, which was ever produced. Even though it is highly toxic to liver, cholesterol ad kidneys.
Comparisons to oral trenbolone
If you take a look at the structure, the first difference is that oral trenbolone is not 17-aa, while metribolone is methylated in a big way. Moreover, on paper metribolone may appear to be hundreds of times more powerful than straight testosterone, but things on paper can be misleading; in fact, those who used metribolone say that it is milder than oral trenbolone, yet it is much more toxic because of the liver strain that occurs.
Methyltrienolone is very different in effect from trenbolone, although they are very similar in structure,. It has a huge anabolic to androgenic ratio in comparison to Steroids like Testosterone, making it possibly the most potent steroid ever. Methyltrienolone is also one of the strongest androgen receptor binder of all steroids. Methyltrienolone required only small doses to see big results in muscle growth and strength. Methyltrienolone does not aromatize to estrogen, but it does have high progestational conversion rate which may increase the effects of estrogen ans prolactine. But anyways, Metribolone causes no water retention, so that ist known for its lean and clean gains.
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